Table 3.

Particle size effects on particle-surfactant interaction

Author/year	Particle composition	Size range	Surfactant	Main findings
Ku et al./2008 [179]	Gelatin particles cross-linked with glutaraldehyde	137, 197, 221, 236, and 287 nm	DPPC monolayer	236 nm particle has the highest affinity towards surfactant
Dwivedi et al./2014 [165]	Poly(organosiloxane)	12nm and 136nm	DPPC monolayer and DPPC/DPPG/SP-C (80:20:0.4 mol%)	Severe inhibition only observed with 136 nm particle
Kodama et al./2014 [130]	Polystyrene	20, 30, 40, 100, 500, and 1000nm	Survanta	Only 20 nm particle eliminates the squeeze-out phase in isotherms and drastically increases the domain fraction of the LC phase
(Simulation) Curtis et al./2015 [173]	Coarse-grained nanoparticles	1, 2, 4, 6, 10, and 25nm	Coarse-grained DPPC bilayer	Hydrophilic particles larger than 2 nm become wrapped while 1 nm particles become embedded