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Anti-aging and antioxidant effect of FLA and p-FLA in C. elegans. (A)–(D): 2 mg/mL p-FLA extracts significantly increased the expression of ins-18, daf-16, let-60 and sir-2.1, which are key anti-aging genes; (E): 2 mg/mL p-FLA extracts up-regulate skn-1 expression; the effect was three times greater than FLA extracts; (F): 2 mg/mL p-FLA extracts increased the expression of antioxidant enzyme sod-1 significantly. Error bars represent means ± SEMs (* p < 0.05, ** p < 0.01).
