Figure 1.
In vivo detection of amyloid plaques (indicated by arrowheads and arrows) in the brain of a Tg2576 mouse after injection with (E,E)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styryl-benzene (FSB) [14]. (a) T1-weighted 1H imaging of the mouse brain. (b) T2-weighted image of the same slice indicating the position of the amyloid-beta plaques. (c) 19F MRI image of the mouse brain after FSB injection. (d) 19F-FSB image overlaid on top of the high-resolution T2-weighted 1H image. Images are reprinted with permission from the publisher [14].