Table 4.

Validation results of artemether and lumefantrine.

Validation Criteria		Artemether		Lumefantrine
Linearity	Slope	0.9986		1.0342
	Intercept	0.0028		0.0001
	R2	0.992		0.993
Trueness	Level	Concentration (mg/mL)	Relative Bias (%)	Concentration (mg/mL)	Relative Bias (%)
	80%	0.08	5.03	0.0096	5.22
	100%	0.10	−0.08	0.0120	1.72
	120%	0.12	0.77	0.0144	0.05
Precision	Level	Repeatability (RSD%)/Intermediate Precision (RSD%)		Repeatability (RSD%)/Intermediate Precision (RSD%)
	80%	2.30/2.40		1.75/1.87
	100%	1.33/2.86		2.36/3.36
	120%	1.18/3.10		0.99/0.99
Accuracy	Level	β-Expectation Tolerance Limits (%)		β-Expectation Tolerance Limits (%)
	80%	[0.62, 9.43]		[1.75, 8.69]
	100%	[−6.30, 6.15]		[−4.92, 8.37]
	120%	[−6.40, 7.93]		[−1.77, 1.87]