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. 2020 Jul 28;25(15):3429. doi: 10.3390/molecules25153429

Figure 4.

Figure 4

Binding modes of compounds 1a (green), 1b (aquamarine blue), and 1c (orange) in the MOR binding site (yellow). The ligands are shown as colored sticks. Several residues and transmembrane helices (relevant for each picture) are shown and labelled. Yellow dotted lines represent interactions. (A) All of the compounds superimposed on DAMGO (pink, from 6DDF [43]). (B) Focus on the C-terminal part and compounds 1a–1c together. (C–E) Focus on the interactions with Y148 and compounds 1a (C), 1b (D), and 1c (E). (F–H) Focus on the C-terminal part and compounds 1a (F), 1b (G), and 1c (H).