Skip to main content
. 2020 Jul 28;25(15):3429. doi: 10.3390/molecules25153429

Table 3.

The effective dose (ED50) of compounds 1a–1d.

Cmpd Compound ED50 ± SEM (nmol/rat) 1
1a H-Tyr-D-Ala-Gly-Phe-NH-N=CH-3,5-(CF3)2Ph 0.18 ± 0.05
1b H-Tyr-D-Ala-Gly-Phe-NH-NH-C(=O)-3,5-(CF3)2Ph n./a 2
1c H-Tyr-D-Ala-Gly-Phe-NH-NH-C(=O)-CH2-3,5-(CF3)2Ph 0.56 ± 0.04
1d H-Tyr-D-Ala-Gly-Phe-NH-NH-C(=O)-NH-N=CH-3,5-(CF3)2Ph 0.32 ± 0.04

1 ED50 (half maximal effective dose) ± standard error of the mean, n = 4–8; 2 n/a—not applicable, as there was no dose dependency the value could not be established.