Table 1.
The summary of described hydrogels, microparticles and fibres for drug delivery based on combination of PLA and its copolymers with different CDs.
| Type of Drug Delivery System |
Platform | Type of CD | Drug | Release Medium |
In Vitro Studies | Ref. |
|---|---|---|---|---|---|---|
| Hydrogel | PLGA-PEG | α-CD | Vitamin B12 | PBS | nd | [19] |
| Hydrogel | PLA-PEG | α-CD | DOX | PBS | HeLa cells | [20] |
| Fibre | PLA | γ-CD | Gallic acid | 10% or 95% EtOH | nd | [21] |
| Fiber | PLA | Mβ-CD | Quercetin | PBS | nd | [22] |
| Fibre | PLA | polyCD | Ciprofloxaxin | PBS | NIH3T3 cells | [23] |
| Microparticle | PLGA | γ-CD | Dexamethasone | PBS | nd | [24] |
| Microparticle | PLGA | DMβ-CD | Celecoxib | PBS | Human chondrocytes | [25] |
| Microparticle | PLGA | HPβ-CD | Prostaglandin | PBS | Calu-3 cells | [26] |
| Nanoparicle | PLGA | HPβ-CD | Triamcinolone acetonide | PBS | Rabbit eyes | [27] |
| Nanoparicle | PLA-PEG | β-CD | Folic acid | nd | HEK293T cells | [28] |
| Nanoparticle | PLA/PEG | β-CD | DOX | pH 6.0, pH 5.5, pH 7.4 | HepG2 cells | [29] |