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. 2020 Jul 27;25(15):3394. doi: 10.3390/molecules25153394

Table 1.

Isolated compounds from different extracts and parts of A. cearensis and related biological activities.

Author (Year) Plant Part Extract Isolated Compounds Activity
Leal et al., 1997 Bark Hydroalcoholic extract Coumarin; isokaempferol, flavonoids (fraction). Hydroalcoholic extract and coumarin: anti-nociceptive; anti-inflammatory
Bravo B. et al., 1999 Bark Dichloromethane extract Coumarin, Amburoside A, Amburoside B. Extract: anti-plasmodium
Coumarin: leishmanicidal, bactericidal and antimalarial
Amburoside A: antimalarial
Leal et al., 2000 Bark Hydroalcoholic extract - Antinociceptive, anti-inflammatory and bronchodilator
Costa-Lotufo, 2003 Bark Methanolic extract kaempferol, isokaempferide, amburoside A and protocatechuic acid Isolated compounds: antiproliferative and antioxidant
Leal et al., 2003a Bark Hydroalcoholic extract Coumarin; 3,4,5-trihydroxi-benzoic acid; isokaempferol; fisetin and a biflavonoid Extract, coumarin and flavonoid fraction: anti-inflammatory; (bronchodilator).
Marinho et al., 2004 Bark Hydroalcoholic extract Coumarin Immunomodulation of specific antibodies; vascular permeability reduction.
Leal et al., 2005 Bark Ethanolic extract Amburoside A Amburoside A: neuroprotective
Leal et al., 2008 Bark Ethanolic extract Amburoside A Hepatoprotective and anti-inflammatory
Farias et al., 2010 Seeds Aqueous extract - Toxicity against Aedes aegypti larvae
Lima et al., 2013 Seeds Aqueous extract - Anti-edematous
Lopes et al., 2013 Bark Ethanolic extract Afrormosin Afrormosin: inhibition of neutrophil responses
Sá et al., 2014 Bark Chloroform extract - Extract: bacteriostatic
Barberino et al., 2015 Leaves Ethanolic extract - Extract: improves in
vitro development of ovine secondary follicles
Gouveia et al., 2016 Leaves Ethanolic extract - Improves in vitro development of
caprine preantral follicles
Pereira et al., 2017a Seeds Ethanolic extract and fractions - Ethanolic extracts and fractions: neuroprotective (glutamate-induced excitotoxicity) to cell lines
Pereira et al., 2017b Seeds Ethanolic extract and fractions - Ethanolic extracts and fractions: neuroprotective (glutamate-induced excitotoxicity) to primary culture
Oliveira et al., 2020 Seeds Protein extract and fractions - Synergistic antibacterial effect against S. aureus and E. coli; trypsin activity inhibitor.