Table III.
Multivariate analysis for predictive factors of epidermal growth factor receptor mutation.
| Factor | Hazard ratio | 95% CI | P-value |
|---|---|---|---|
| Smoking status | |||
| Never-smokeda | 1.00 | – | – |
| Ex-smoker | 0.85 | 0.07-1.97 | 0.245 |
| Regular smoker | 0.71 | 0.11-1.70 | 0.224 |
| SUVmax, primary lesion | |||
| SUVmax≤5a | 1.00 | – | – |
| 5<SUVmax≤10 | 3.68 | 0.01-1.05 | 0.055 |
| 10<SUVmax≤15 | 6.33 | 0.01-0.52 | 0.012 |
| SUVmax>15 | 19.50 | 0.00-0.02 | <0.001 |
| SUVmax, metastatic lymph nodes | |||
| SUVmax≤5a | 1.00 | – | – |
| 5<SUVmax≤10 | 0.66 | 0.06-0.88 | 0.032 |
| SUVmax>10 | 0.85 | 0.02-0.64 | 0.013 |
| CEA, ng/ml | |||
| CEA≤5a | 1.00 | – | – |
| 5<CEA≤10 | 0.73 | 1.00-1.73 | 0.227 |
| 10<CEA≤15 | 1.16 | 0.61-56.94 | 0.127 |
| CEA>15 | 0.64 | 0.66-8.03 | 0.193 |
| Histology type | |||
| Squamous cell carcinomaa | 1.00 | – | – |
| Adenocarcinoma | 3.20 | 0.35-29.26 | 0.303 |
a
Hazard Ratio of the factor is set to 1. CI, confidence interval; SUVmax, maximum standardized uptake value; CEA, carcinoembryonic antigen.