Table IV.

Comparative receiver operating characteristic analysis of predictive factors to discriminate epidermal growth factor receptor mutation.

Predictive factors	AUC	95% CI	Sensitivity, %	Specificity, %	P-value
SUVmax(T)	0.830	0.768-0.892	87.7	63.8	<0.001
SUVmax(N)	0.777	0.634-0.842	88.2	53.2	<0.001
CEA	0.632	0.546-0.719	68.1	67.0	<0.001
SUVmax(T)+SUVmax(N)	0.876	0.821-0.930	82.4	81.3	<0.001
SUVmax(T)+SUVmax(N)+CEA	0.877	0.824-0.931	85.3	75.1	<0.001
SUVmax(T)+SUVmax(N)+CEA+smoking status	0.886	0.835-0.937	82.1	80.3	<0.001

SUV_max, maximum standardized uptake value; CEA, carcinoembryonic antigen; CI, confidence interval; AUC, area under the curve, SUV_max(T), SUV_max in primary lesions; SUV_max(N), SUV_max in metastatic lymph nodes.