Figure 2:

Epigenetic alterations in maspin. (A) Maspin promoter fragment analysis and methylation status by methyl-specific-PCR performed in human benign prostate tissue and cancer specimens of various Gleason score. Green box indicate, no fragment deletion and methylation, whereas red box indicate promoter fragment deletion. (B) Mean methylation difference of maspin in the Cancer Genome Atlas Prostate Adenocarcinoma (TCGA-PRAD) data between normal and prostate tumor samples. No statistical difference was noted between the two groups.