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. Author manuscript; available in PMC: 2021 Jul 6.
Published in final edited form as: Mol Psychiatry. 2020 Jan 6;26(8):3751–3764. doi: 10.1038/s41380-019-0637-4

Figure 4. Effect of MAALIN in vitro overexpression and knock out on MAOA expression in NPCs 35 days post differentiation.

Figure 4.

a–f, Fluorescence-Activated Cell Sorting (FACS) plots showing NPCs selected on size and internal complexity (a-c). The population in c was sorted independently according to high-intensity GFP expression vs. no or low-intensity GFP expression in NPCs transfected with the (d) HSV-MAALIN-GFP virus, (e) mock transfected, and (f) untransfected. Mock transfected and untransfected cells showed no GFP fluorescence. g, Relative MAOA expression in FACS-sorted NPCs. h, Relative MAALIN and MAOA expression in NPCs following MAALIN knock out. Bars represent fold change expression relative to GFP expression levels. Error bars represent SEM. **p<1.0×10−4 ***p<5.0×10−13.