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. 2020 Aug 25;27(10):963–973. doi: 10.1111/acem.14104

Table 4.

Multivariable Regression for Critical Illness

N (%) OR (95% CI)
Age group (years)
19–44 367 (24.7) Reference
45–54 298 (20.1) 1.07 (0.74–1.55)
55–64 307 (20.7) 0.99 (0.68–1.44)
65–74 263 (17.7) 1.01 (0.67–1.52)
75 or older 367 (24.7) 0.81 (0.51–1.28)
Sex
Female 691 (46.6) Reference
Male 792 (53.4) 1.45 (1.12–1.88)
Race
White 362 (24.4) 0.86 (0.61–1.19)
African American 554 (37.4) Reference
Other 432 (29.1) 1.21 (0.90–1.63)
Comorbidities
COPD 84 (5.7) 1.50 (0.87–2.58)
Hypertension 897 (60.5) 1.23 (0.91–1.67)
Hyperlipidemia 592 (39.9) 1.17 (0.87–1.56)
Diabetes mellitus 634 (42.8) 1.21 (0.93–1.58)
Prior CVA 121 (8.2) 1.43 (0.91–2.25)
Congestive heart failure 218 (14.7) 1.45 (1.00–2.12)
Chronic kidney disease 306 (20.6) 0.89 (0.60–1.32)
Current ESRD 106 (7.1) 1.14 (0.67–1.97)
Obstructive sleep apnea 154 (10.4) 1.58 (1.07–2.33)
Blood‐borne cancer 18 (1.2) 3.53 (1.26–9.86)
Symptoms
Anosmia 104 (9.4) 1.06 (0.63–1.78)
Cough 800 (71.9) 0.95 (0.70–1.30)
Headache 43 (3.9) 0.69 (0.29–1.65)
Myalgias 246 (22.1) 0.89 (0.62–1.28)
Labs
WBC 
≥10 339 (24.1) 1.58 (1.15–2.17)
≤ 4 144 (10.2) 1.00 (0.65–1.54)
ALC ≤ 1.5 1,108 (79.1) 1.00 (0.71–1.40)
ANC/ALC ≥ 6 569 (40.6) 1.61 (1.20–2.17)
Total bilirubin > 1.3 82 (6.2) 1.02 (0.61–1.71)
Albumin < 3.5 780 (58.8) 1.80 (1.39–2.32)
AST > 40 657 (49.5) 1.66 (1.20–2.29)
ALT > 40 466 (35.3) 0.88 (0.63–1.22)
LDH  ≥ 245 605 (86.4) 1.14 (0.66–1.97)
Lactate  ≥ 2 259 (29.7) 1.95 (1.40–2.73)
D‐dimer > 0.49 323 (79.4) 1.44 (1.05–1.97)
C‐reactive protein >8 633 (98.3) 1.41 (0.95–2.11)
Ferritin > 300 (men) or 150 (women) 563 (81.1) 1.14 (0.69–1.87)
Troponin > 0.9 87 (22.3) 3.65 (2.03–6.57)

BMI = body mass index; CVA = cerebrovascular accident; ESRD = end‐stage renal disease (on dialysis); HIV = human immunodeficiency virus.