TABLE 1.

Characteristics of the patients

Patient	1	2	3
Age	23	44	23
Sex	Female	Male	Female
Blood group	A Positif ccee Kell négatif	AB Positif ccee Kell négatif	A Négatif ccee Kell négatif
Hemoglobinopathy	SS (Bantu phenotype)	SS (Bantu phenotype) and Alpha Thalassemia trait	SS (Bantu phenotype) and G6PD deficiency
Origin	Congo	Congo	Congo
HTA	No	Yes	No
Obesity	No	No	No
Hydroxyurea	Yes low Compliance	Yes	Yes
Aspirin	Yes	No	No
Regular exchange therapy	Yes	No	No
Deferasirox	No	No	Yes
COVID ‐19 diagnosis	PCR	PCR	PCR
Lung lesion at entry	Unilateral ground glass	Mild typical COVID lesion	Pneumomediastin ; no lung lesion
Length of PCR positivity			> 30 days
Respiratory symptoms	Cough	Cough	None
Others symptoms	Abdominal pain, weight loss	Leg ulcer	Dehydration after vomiting
Deep venous thrombosis	No	No	localized DVT catheter site 11 days after ET
Renal insufficiency	No	Yes but already basal	Acute and reversible
Intensive care	No	No	No
Exchange therapy	Regular, one during COVID	2 during COVID	1 ( suspected DHTR)
Hydroxychloroquin	No	400 mg x 2/d then 200 mg x2/d 5 d	No
Anticoagulants	No	No (renal insufficiency)	enoxaparin 40 mg/d prophylactic, then after DVT tinzaparin 175 U/kg