Table 4.
Biochemical parameters of the COVID‐19, control, common COVID‐19, and severe COVID‐19 groups
| COVID‐19 (N = 169) | Controls (N = 80) | Statistics | P a | Common group (N = 145) | Severe group (N = 24) | Statistics | P b | |
|---|---|---|---|---|---|---|---|---|
| TP | 70.62 ± 5.94 | 76.15 ± 4.27 | t = −8.369 | .000 | 71.08 ± 5.94 | 67.82 ± 5.23 | t = 2.529 | .012 |
| ALB | 41.39 ± 4.25 | 45.06 ± 2.25 | t = −8.908 | .000 | 41.80 ± 4.12 | 38.87 ± 4.21 | t = 3.222 | .002 |
| GLB | 29.23 ± 3.84 | 31.09 ± 3.30 | t = −3.723 | .000 | 29.28 ± 3.87 | 28.95 ± 3.69 | t = 0.403 | .687 |
| ALT | 21.1 (13.0‐32.0) | 19.0 (14.0‐28.8) | Z = −0.641 | .522 | 18.0 (13.0‐29.0) | 31.2 (24.3‐61.6) | Z = −3.864 | .000 |
| AST | 24.0 (19.0‐34.1) | 19.5 (17.0‐23.0) | Z = −4.953 | .000 | 23.0 (19.0‐31.0) | 35.1 (26.3‐46.0) | Z = −3.648 | .000 |
| GGT | 27.0 (16.0‐56.5) | 20.0 (15.3‐32.8) | Z = −1.499 | .134 | 25.0 (15.0‐48.5) | 55.5 (25.0‐157.8) | Z = −3.929 | .000 |
| ALP | 54.0 (41.0‐64.0) | 71.0 (62.0‐86.3) | Z = −6.792 | .000 | 54.0 (41.0‐63.5) | 55.5 (40.6‐70.0) | Z = −0.419 | .675 |
| TBIL | 11.3 (8.6‐15.2) | 15.2 (13.1‐19.8) | Z = −5.912 | .000 | 11.0 (8.5‐15.1) | 12.3 (8.8‐15.4) | Z = −0.669 | .504 |
| SCr | 65.0 (55.0‐79.5) | 58.5 (51.3‐72.8) | Z = −2.244 | .025 | 64.7 (54.0‐79.5) | 71.3 (62.5‐80.8) | Z = −1.552 | .121 |
| BUN | 3.7 (3.1‐4.4) | 4.7 (3.6‐5.4) | Z = −5.436 | .000 | 3.6 (3.1‐4.3) | 4.2 (3.2‐4.7) | Z = −1.586 | .113 |
| CK | 70.7 (48.2‐113.5) | 95.8 (73.0‐115.0) | Z = −3.569 | .000 | 70.2 (47.0‐106.0) | 90.5 (66.8‐210.2) | Z = −2.567 | .010 |
| CK‐MB | 12.3 (9.4‐15.7) | 12.5 (10.0‐15.0) | Z = −0.134 | .894 | 12.3 (9.4‐15.1) | 12.9 (9.0‐16.4) | Z = −0.401 | .689 |
| LDH | 203.0 (164.5‐256.3) | 189.5 (165.8‐210.0) | Z = −2.127 | .033 | 198.0 (159.0‐235.5) | 272.0 (221.2‐340.8) | Z = −4.195 | .000 |
| TC | 3.78 ± 0.87 | 4.96 ± 0.83 | t = −10.000 | .000 | 3.82 ± 0.87 | 3.58 ± 0.87 | t = 1.259 | .210 |
| TG | 1.1 (0.9‐1.7) | 1.2 (0.9‐1.9) | Z = −0.664 | .507 | 1.1 (0.9‐1.7) | 1.1 (0.8‐1.6) | Z = −0.432 | .665 |
| CRP | 10.8 (3.0‐25.8) | 0.3 (0.2‐1.3) | Z = −9.701 | .000 | 7.9 (2.3‐21.1) | 37.2 (22.3‐61.8) | Z = −4.855 | .000 |
Note: Data were expressed as mean (SD) and medians (P25, P75).
Abbreviations: ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CK, creatine kinase; CK‐MB, creatine kinase‐myocardial band; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; GGT, gamma‐glutamyl transferase; GLB, globulin; LDH, lactate dehydrogenase; SCr, serum creatinine concentration; TBil, total bilirubin; TC, total cholesterol; TG, triglyceride; TP, total protein.
a
Comparison between the COVID‐19 and control groups.
b
Comparison between common COVID‐19 and severe COVID‐19 groups.