Table 5.
Biochemical parameters of the common COVID‐19 and severe COVID‐19 groups
| Common group (N = 145) | Severe group (N = 24) | χ 2 | P a | ||||||
|---|---|---|---|---|---|---|---|---|---|
| All patients N (%) | Overall N (%) | Below the lower reference limit N (%) | Above the higher reference limit N (%) | Overall N(%) | Below the lower reference limit N (%) | Above the higher reference limit N (%) | |||
| TP | 27 (16.0) | 20 (13.8) | 19 (13.1) | 1 (0.7) | 7 (29.2) | 7 (29.2) | 0 (0) | 2.571 | .109 |
| ALB | 56 (33.1) | 42 (29.0) | 42 (29.0) | 0 (0) | 14 (58.3) | 14 (58.3) | 0 (0) | 8.016 | .005 |
| GLB | 2 (1.2) | 2 (1.4) | 0 (0) | 2 (1.4) | 0 (0) | 0 (0) | 0 (0) | 0.000 | 1.000 |
| ALT | 32 (18.9) | 25 (17.2) | 5 (3.5) | 20 (13.8) | 7 (29.2) | 0 (0) | 7 (29.2) | 1.210 | .271 |
| AST | 36 (21.3) | 24 (16.6) | 2 (1.4) | 22 (15.2) | 12 (50.0) | 1 (4.2) | 11 (45.8) | 13.742 | .000 |
| GGT | 44 (26.0) | 32 (22.1) | 2 (1.4) | 30 (20.7) | 12 (50.0) | 0 (0) | 12 (50.0) | 8.342 | .004 |
| ALP | 35 (20.7) | 27 (18.6) | 24 (16.6) | 3 (2.1) | 8 (33.3) | 6 (25.0) | 2 (8.3) | 2.714 | .099 |
| TBIL | 22 (13.0) | 19 (13.1) | 8 (5.5) | 11 (7.6) | 3 (12.5) | 1 (4.2) | 2 (8.3) | 0.000 | 1.000 |
| SCr | 9 (5.3) | 6 (4.1) | 4 (2.8) | 2 (1.4) | 3 (12.5) | 2 (8.3) | 1 (4.2) | 1.438 | .230 |
| BUN | 78 (46.2) | 69 (47.6) | 68 (46.9) | 1 (0.7) | 9 (37.5) | 9 (37.5) | 0 (0) | 0.843 | .359 |
| CK | 26 (15.4) | 20 (13.8) | 16 (11.0) | 4 (2.8) | 6 (25.0) | 0 (0) | 6 (25.0) | 1.219 | .270 |
| CK‐MB | 10 (5.9) | 8 (5.5) | 0 (0) | 8 (5.5) | 2 (8.3) | 0 (0) | 2 (8.3) | 0.006 | .941 |
| LDH | 50 (29.6) | 35 (24.1) | 4 (2.8) | 31 (21.4) | 15 (62.5) | 0 (0) | 15 (62.5) | 14.546 | .000 |
| TC | 40 (23.7) | 32 (22.1) | 25 (17.2) | 7 (4.8) | 8 (33.3) | 7 (29.2) | 1 (4.2) | 1.446 | .229 |
| TG | 39 (23.1) | 35 (24.1) | 2 (1.4) | 33 (22.8) | 4 (16.7) | 0 (0) | 4 (16.7) | 0.648 | .421 |
| CRP | 87 (51.5) | 66 (45.5) | 0 (0) | 66 (45.5) | 21 (87.5) | 0 (0) | 21 (87.5) | 14.530 | .000 |
Abbreviations: ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CK, creatine kinase; CK‐MB, creatine kinase‐myocardial band; COVID‐19, coronavirus disease 2019; CRP, C‐reactive protein; GGT, gamma‐glutamyl transferase; GLB, globulin; LDH, lactate dehydrogenase; SCr, serum creatinine concentration; TBil, total bilirubin; TC, total cholesterol; TG, triglyceride; TP, total protein.
a
Comparison of total abnormal rate between common and severe groups.