Table 4.
Risk Factors of Elevated ALT (>40 U/L) During Hospitalization in Patients With COVID‐19
| Variables | Univariate | Multivariate | |||
|---|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | ||
| Age | |||||
| ≤50 years | Reference | ||||
| >50 years | 1.847 (1.120, 3.047) | 0.016 | 2.077 (1.183, 3.648) | 0.011 | |
| Sex | |||||
| Female | Reference | ||||
| Male | 1.753 (1.090, 2.819) | 0.021 | 1.646 (0.975, 2.778) | 0.062 | |
| BMI | |||||
| <28 kg/m2 | Reference | ||||
| ≥28 kg/m2 | 2.467 (1.205, 5.052) | 0.014 | 0.901 (0.360, 2.258) | 0.825 | |
| NAFLD | |||||
| No | Reference | ||||
| Yes | 2.962 (1.745, 5.028) | <0.001 | 2.956 (1.526, 5.726) | 0.001 | |
| Severe illness | |||||
| No | Reference | ||||
| Yes | 6.133 (2.259, 16.652) | <0.001 | 4.009 (0.966, 16.638) | 0.056 | |
| ICU | |||||
| No | Reference | ||||
| Yes | 4.338 (1.391, 13.530) | 0.011 | 0.931 (0.175, 4.946) | 0.933 | |
| Hypertension | |||||
| No | Reference | ||||
| Yes | 0.576 (0.297, 1.116) | 0.102 | |||
| Diabetes | |||||
| No | Reference | ||||
| Yes | 0.842 (0.343, 2.067) | 0.708 | |||
| Atomized inhalation of IFNα‐2b | |||||
| No | Reference | ||||
| Yes | 0.389 (0.239, 0.633) | <0.001 | 0.402 (0.236, 0.683) | 0.001 | |
| Lopinavir/ritonavir | |||||
| No | Reference | ||||
| Yes | 1.244 (0.733, 2.111) | 0.418 | |||
| Arbidol | |||||
| No | Reference | ||||
| Yes | 1.218 (0.761, 1.949) | 0.411 | |||