Table 1.
Possible therapeutics for COVID‐19 during Pregnancy
| Description | Licensed for | Administration | Status of Use in Japan | Indication for pregnant patients | |
|---|---|---|---|---|---|
| Corticosteroids | Analogues of steroid hormones | Bronchial asthma etc. | Inhalted | Ongoing clinical trial | Yes |
| Hydroxy chloroquine | Malaria, Systemic lupus erythematosus | Malaria, SLE etc. | Oral or intravenous | Ongoing clinical trial | Yes |
| Ritonavir+Lopinavir(Kaletra) | Protease inhibitors | HIV/AIDS | Oral | Ongoing clinical trial | Yes |
| Favipiravir (Avigan) | RNA polymerase inhibitor | Influenza | Oral | Ongoing clinical trial |
No (teratogenous) |
| Convalescent plasma | Polyclonal human antibodies | Intravenous | Not obtainable in Japan | Yes | |
| Remdesivir | RNA polymerase inhibitor | Various RNA virus infections | Intravenous | Covered by National Health Insurance | Yes |
| Tocilizumab | Anti IL‐6 monoclonal Ab | Rheumatoid arthritis | Intravenous | Ongoing clinical trial | Yes |