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. 2020 Aug 25;93(3):1449–1458. doi: 10.1002/jmv.26424

Table 2.

Significant factors associated with severe COVID‐19 illnessa

Coefficient 95% CI P
Diabetes 23.4 14.99‐31.7 <.0001
Malignancy 23.4 9.9‐36.9 .0007
Cerebrovascular disease 19.6 2.6‐36.6 .02
Hypertension 5.1 1.1‐9.1 .01
Immunosuppressed 53.9 31.3‐76.4 <.0001
Time from illness onset to first hospital admission, d 0.4 0.1‐0.6 .0008
Shortness of breath 5.4 4.1‐6.7 <.0001
Vomiting 11.4 0.2‐22.7 .05
Abdominal pain 24.7 17.4‐31.9 <.0001
Fatigue 1.7 0.3‐3.0 .01
Chest pain 4.5 1.8‐7.1 .001
Nausea 8.8 0.2‐17.4 .05
Respiratory failure 1.4 0.6‐2.3 .001
Lymphocyte count, g/L −2.2 −4.3‐(−0.2) .04
Neutrophil count, g/L 0.6 0.2‐0.9 .0008
Albumin, µmol/L −0.2 −0.3‐(−0.1) .0009
C‐reactive protein, mg/L 0.02 0.01‐0.04 .007

Abbreviations: ATS, American Thoracic Society; CI, confidence interval; COVID‐19, coronavirus disease 2019; IDSA, Infectious Disease Society of America; WHO, World Health Organization.

a

Severe COVID‐19 disease definition based on the WHO Interim Guidance Report or IDSA/ATS criteria for severe pneumonia. 12 , 13