Table I.
Association between miR-375-3p expression and clinicopathological characteristics of patients with laryngeal squamous cell carcinoma (n=50).
| Characteristics | Number of patients, n | High miR-375-3p expression, n | Low miR-375-3p expression, n | P-value |
|---|---|---|---|---|
| Age, years | 0.571 | |||
| ≤60 | 15 | 5 | 10 | |
| >60 | 35 | 10 | 25 | |
| Sex | 0.632 | |||
| Male | 26 | 8 | 18 | |
| Female | 24 | 7 | 17 | |
| Tumor size, cm | <0.001a | |||
| ≤4 | 25 | 13 | 12 | |
| >4 | 25 | 2 | 23 | |
| Lymph node metastasis | <0.001a | |||
| Negative | 22 | 10 | 12 | |
| Positive | 28 | 5 | 23 | |
| Histological grade | <0.001a | |||
| High | 30 | 10 | 20 | |
| Poor | 20 | 5 | 15 | |
| TNM stage | <0.001a | |||
| I–II | 26 | 11 | 15 | |
| III–IV | 24 | 4 | 20 |
a
P<0.001. miR, microRNA; TNM, tumor-node-metastasis.