TABLE 4.

Risk factors associated with mortality in kidney transplant patients hospitalized for COVID-19

	Univariate HR (95% CI)	P-value	Multivariate HR (95% CI)	P-value
Age	1.101 (1.057-1.157)	<.001	1.103 (1.048-1.162)	<.001
ARDS day 0	3.923 (1.641-3.942)	.002	2.091 (1.031-8.233)	.044
Pulmonary disease	2.891 (1.311-6.392)	.009	1.544 (0.592-4.026)	.375
LDH day 0	1.004 (1.002-1.006)	<.001	1.003 (1-1.005)	.024
Day 3	1.003 (1.000-1.006)	.016
Day 9	1.002 (1.000-1.004)	.03
Day 15	1.004 (1.000-1.007)	.026
CRP day 0	1.003 (1.002-1.005)	<.001	—
Ferritin day 0	1.001 (1.000-1.001)	.056	—
Lymphocytes
Day 6	0.998 (0.996-1)	.018	—
Day 9	0.997 (0.995-0.999)	.007
Day 12	0.997 (0.995-0.999)	.014

Note: Adjusted and nonsignificant for sex; race; repeat transplant; induction therapy; maintenance immunosuppression without mTOR inhibitors; heart disease; AKI stage 3 vs others; AKI 2 and 3 stages vs others; hypertension; use of ACEi/ARB; diabetes; obesity; basal lymphopenia; lymphocyte days 0, 3, and 15; serum creatinine; white blood cells; hemoglobin; D-dimer; ALT; LDH days 6-12; ferritin rest of the days; platelets; tacrolimus levels; diarrhea at admission; fever at admission; cough at admission; myalgia at admission; anticoagulation; time after transplant; days from symptoms onset to admission; nosocomial infection.

Abbreviations: ARDS, acute respiratory distress syndrome; CRP, C-reactive protein; CI, confidence interval; LDH, lactate dehydrogenase; HR, hazard ratio.