Table I.

Roles of different lncRNAs in glioma hallmarks.

lncRNA	Expression in glioma	Maintenance of growth signals	Resistance to growth inhibition signals	Resistance to apoptosis	Ability to replicate indefinitely	Angiogenesis	Invasion	Reprogramming of energy metabolism	Evading immune cell attack	(Refs.)
H19	↑	+		+		+	+			(21,52,69, 72,73,91)
XIST	↑	+								(23,24)
HOXD-AS1	↑	+					+			(25)
CCAT1	↑	+		+			+			(26)
LOC728196	↑	+					+			(27)
PLAC2	↓		–							(31)
PTENP1	↓		–							(32)
HOXA11-AS	↑	+	+	+			+			(33,76)
Plncrna-1	↑	+	+				+			(34–37)
ADAMTS9-AS2	↓		–							(38)
CASC2	↑		+				+			(39)
ANRIL	↑			+						(41)
SNHG3/6/16/2O	↑	+		+						(47–50)
TUG1	↓			–					–	(51,82)
CASC7	↓		–	–						(53)
GHET1	↑			+			+			(54)
MALAT1	↑	+			+					(56,57)
FOXD2-AS1	↑	+			+		+			(59–61)
TUG1	↑					+				(62)
PVT1	↑	+		+			+			(64–66,93)
AB073614	↑	+					+			(67,68)
TSLC1-AS1	↓		–				–			(69)
DANCR	↑			+			+			(71,75)
CCND2-AS1	↑						+			(72)
UCA	↑	+		+			+			(78)
TP53TG1	↑							+		(79)
LINC00152	↑	+					+		+	(82,89)
PGM5-AS1	↑								+	(83)
ST20-AS1	↑								+	(83)
AGAP2-AS1	↑								+	(83)
MIR155HG	↑								+	(83)
SNHG8	↓								–	(83)
LINC00937	↓								–	(83)
MAPKAPK5-AS1	↓								–	(83)
HCG18	↓								–	(83)

↑, increased expression; ↓, decreased expression; +, promoting effect; −, inhibitory effect; lncRNA, long non-coding RNA.