Table 2.
Pre-treatment vs post-treatment comparison in clinical and biochemical parameters in whole studied population
| Variable | Initial n = 40 | Final n = 40 | p value |
|---|---|---|---|
| Gender | |||
| Female (N %) | 24 (60) | – | |
| Male (N %) | 16 (40) | – | |
| Age (years) | 55.9 ± 10.0 | – | |
| BMI (kg/m2) | 29.0 ± 6.1 | 28.8 ± 5.8 | 0.539 |
| uOC (ng/dL) | 2.7 ± 1.5 | 2.3 ± 1.3 | 0.104 |
| cOC (ng/dL) | 0.701 ± 0.591 | 0.945 ± 0.753 | 0.004 |
| uOC/cOC index | 6.0 ± 5.5 | 3.4 ± 2.2 | 0.001 |
| Insulin (ng/dL) | 103.7 ± 59.6 | 97.2 ± 49.9 | 0.428 |
| Glucose (mg/dL) | 137.6 ± 31.4 | 123.1 ± 28.7 | 0.001 |
| HOMA-IR | 3.5 ± 2.2 | 3.0 ± 1.7 | 0.040 |
| % FPβC | 559 ± 373 | 231 ± 169 | 0.001 |
| SBP (mmHg) | 133 ± 21 | 128 ± 18 | 0.082 |
| DBP (mmHg) | 83 ± 12 | 80 ± 12 | 0.030 |
| Cholesterol (mg/dL) | 198 ± 34 | 199 ± 40 | 0.625 |
| Triglycerides (mg/dL) | 189 ± 21 | 191 ± 90 | 0.624 |
| VLDL (mg/dL) | 38 ± 25 | 38 ± 18 | 0.624 |
uOC undercarboxylated osteocalcin, cOC carboxilated osteocalcin, HOMA-IR homeostatic model assessment-insulin resistance, SBP systolic blood pressure, DBP diastolic blood pressure, FPβC functional pancreatic β cells. Data presented as average and standard deviation. Statistically significant data are shown in italics type (p < 0.05)