Table 1.
Effect of curcumin on the levels of MDA, GSH, SOD and GSH-Px in cerebral homogenates prepared from ACR intoxicated rats (n = 10, mean ± SD)
| Groups | MDA (nmol/mg prot) |
GSH (mg/g prot) |
SOD (U/mg prot) |
GSH-Px (U/mg prot) |
|---|---|---|---|---|
| Normal | 0.425 ± 0.141 | 4.41 ± 0.58 | 60.21 ± 5.38 | 14.81 ± 1.95 |
| ACR | 1.133 ± 0.352 ** | 2.30 ± 0.47** | 52.72 ± 6.94 ** | 10.36 ± 1.84 ** |
| ACR + curcumin 50 mg/kg | 0.918 ± 0.322 | 2.77 ± 0.46 # | 53.89 ± 8.02 | 12.58 ± 1.96 # |
| ACR + curcumin 100 mg/kg | 0.854 ± 0.216 # | 2.92 ± 0.59 # | 59.16 ± 6.46 # | 13.15 ± 1.87 ## |
**P < 0.01 compared to the corresponding control rats. # P < 0.05, ## P < 0.01; compared with the corresponding ACR group