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. 2020 Aug 18;22:90. doi: 10.1186/s13058-020-01327-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Haematoxylin and eosin stains of formalin-fixed paraffin-embedded tissue sections collected from breast cancer patients. FFPE tissue blocks were retrieved from 46 patients, and haematoxylin and eosin stains were performed to confirm the presence of malignant breast disease. Examples of a normal breast tissue, b carcinoma in situ and c invasive carcinoma. Samples that did not contain invasive disease were excluded from analysis. d, e Haematoxylin and eosin stain of a core biopsy and corresponding surgically excised tumour from a patient with a grade 3 invasive ductal carcinoma. Bars represent 200 μM