Table 4.
A. All Patients (N = 234) | |||
---|---|---|---|
Variable | Odds ratio | 95% Confidence interval | P |
A.1. Univariate Logistic regression | |||
Age | 0.95 | 0.92-0.97 | <0.0001 |
Race (vs White) | |||
Black | 0.23 | 0.12-0.45 | <0.0001 |
Asian | 1.25 | 0.13-12.31 | 0.85 |
Sex (F vs M) | 1.76 | 1.002-3.09 | 0.049 |
Uni/Uni (vs discordant AVS) | 2.34 | 1.25-4.11 | 0.005 |
LI baseline | 1.003 | 1.00-1.01 | 0.317 |
LI post-ACTH | 1.02 | 1.005-1.02 | 0.004 |
CI baseline | 0.82 | 0.69-0.99 | 0.038 |
CI post-ACTH | 0.26 | 0.14-0.48 | <0.0001 |
Mutation (vs CACNA1D) | |||
KCNJ5 | 7.47 | 1.82-30.65 | 0.01 |
ATP1A1 | 4.00 | 0.73-21.84 | 0.20 |
ATP2B3 | 0.27 | 0.03-2.9 | 0.04 |
Dominant side, Left | 3.62 | 2.08-6.31 | <0.0001 |
A.2. Multivariate Logistic regression | |||
Age | 0.94 | 0.92-0.98 | 0.0004 |
Dominant side, Left | 3.53 | 1.72-7.22 | <0.0001 |
CI post-ACTH | 0.24 | 0.1-0.54 | <0.0001 |
Race | 0.0107 | ||
Black | 0.28 | 0.12-0.66 | |
Asian | 0.56 | 0.05-6.19 | |
B. Patients with biochemical benefit (N = 99) | |||
Multivariate Logistic regression | |||
Age | 0.94 | 0.90-0.99 | 0.012 |
CI post-ACTH | 0.14 | 0.03-0.66 | 0.014 |
Abbreviations: AVS, adrenal vein sampling; CI, contralateral suppression index; F, female; LI, lateralization index; M, male; Uni, unilateral.