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. 2020 Aug 12;12:233. doi: 10.3389/fnagi.2020.00233

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Copyright © 2020 Choi, Lee, Choi, Seo, Choo, Kim, Song, Choi, Cho, Kim and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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APOE ε4 effects on the aging slopes of women. The pairs showing group differences were Caucasian APOE ε4 carriers vs. Korean non-carriers or carriers. The aging slopes of females were compared among the four groups: Caucasian APOE ε4 carriers and non-carriers and Korean APOE ε4 carriers and non-carriers. The aging slopes and the confidence intervals (CIs) were estimated based on 10,000 bootstrap iterations of linear regression analysis using each regional volume relative to ICV as a dependent variable. Asterisk denotes non-overlap of two CIs or statistical significance.