Table 1.
Cohort sizes and demographics for the Korean and Caucasian datasets.
| Cohort | Subjects | Age | MMSE | Education | APOE | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sex | n | Mean (y) | SD | Mean | SD | Mean (y) | SD | n | ε4 (%) | |
| Korean (GARD) | F | 638 | 72.1 | 4.3 | 27.1 | 2.2 | 8.4 | 4.1 | 534 | 17.0 |
| M | 370 | 74.3 | 5.0 | 27.8 | 1.6 | 12.2 | 4.0 | 296 | 17.6 | |
| Caucasian (ADNI) | F | 163 | 74.5 | 4.8 | 29.2 | 1.1 | 15.5 | 2.6 | 161 | 29.2 |
| M | 179 | 75.6 | 5.2 | 29.0 | 1.1 | 17.0 | 2.6 | 179 | 24.6 | |
| Two-way ANOVA (ethnicity, sex) | F | p | F | p | F | p | F | p | ||
| Ethnicity | 54.9 | <0.001 | 235.1 | <0.001 | 778.1 | <0.001 | 13.8 | <0.001 | ||
| Sex | 48.6 | <0.001 | 27.3 | <0.001 | 235.8 | <0.001 | 0.2 | 0.659 | ||
| Ethnicity*sex | 3.5 | 0.063 | 15.5 | <0.001 | 24.7 | <0.001 | 0.9 | 0.323 | ||
GARD, Gwangju Alzheimer’s & Related Dementia, Korea; ADNI, Alzheimer’s Disease Neuroimaging Initiative; MMSE, mini mental state examination; APOE, apolipoprotein E gene; F, female; M, male; y, years.