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. 2020 Aug 12;12:233. doi: 10.3389/fnagi.2020.00233

Table 3.

Ethnicity and sex differences in aging slopes of cortical and subcortical structures.

Female Male
Caucasian Korean Caucasian Korean
Slope 95% CI Slope 95% CI Slope 95% CI Slope 95% CI
Brain volume −0.791 [−1.152, −0.574] −0.408 [−0.486, −0.329] −0.612 [−0.760, −0.457] −0.513 [−0.598, −0.428]
Cortical volumes
   Frontal −0.664 [−1.018, −0.342] −0.155 [−0.257, −0.050] −0.491 [−0.741, −0.245] −0.323 [−0.422, −0.221]
   Temporal −0.941 [−1.268, −0.632] −0.439 [−0.544, −0.338] −0.684 [−0.955, −0.433] −0.570 [−0.691, −0.456]
   Parietal −0.828 [−1.141, −0.517] −0.207 [−0.315, −0.098] −0.584 [−0.848, −0.315] −0.349 [−0.473, −0.222]
   Occipital −1.114 [−1.541, −0.722] −0.344 [−0.480, −0.205] −0.615 [−0.903, −0.309] −0.659 [−0.820, −0.496]
   Cingulate −0.649 [−1.069, −0.275] −0.218 [−0.364, −0.074] −0.196 [−0.460, 0.059] −0.347 [−0.515, −0.182]
   Insular −0.478 [−0.835, −0.145] 0.025 [−0.105, 0.162] −0.130 [−0.448, 0.177] −0.048 [−0.203, 0.110]
Subcortical volumes
   Ventricle 2.187 [0.549, 3.741] 4.176 [3.527, 4.815] 2.869 [1.935, 3.904] 2.796 [2.181, 3.427]
   Thalamus −0.832 [−1.286, −0.534] −0.210 [−0.381, −0.023] −0.490 [−0.774, −0.207] −0.406 [−0.605, −0.205]
   Putamen −0.550 [−1.058, 0.008] −0.734 [−0.960, −0.500] −0.496 [−0.835, −0.136] −0.714 [−0.976, −0.441]
   Hippocampus −1.588 [−2.074, −1.122] −0.886 [−1.057, −0.723] −1.220 [−1.605, −0.825] −0.977 [−1.193, −0.761]
   Caudate −0.010 [−0.520, 0.571] −0.144 [−0.322, 0.036] −0.058 [−0.433, 0.351] −0.236 [−0.476, 0.003]
   Amygdala −1.697 [−2.375, −1.078] −0.652 [−0.835, −0.468] −1.046 [−1.558, −0.531] −0.918 [−1.159, −0.683]
   Pallidus −0.243 [−0.664, 0.187] 0.383 [0.140, 0.613] −0.183 [−0.493, 0.149] 0.236 [−0.089, 0.575]
   Accumbens −1.635 [−2.409, −0.759] −1.465 [−1.784, −1.147] −1.602 [−2.345, −0.932] −1.137 [−1.502, −0.772]

Values are presented in % per year, and based on 10,000 iterations of linear regression analysis. Slope is presented in bold if the 95% confidence interval (CI) does not include the value of zero.