Table 4.
Correlation between the Studied Markers and the Clinico-Pathological Features of the HCC Patients
| Characteristics | Adiponectin | p | Leptin | p | Visfatin | p |
|---|---|---|---|---|---|---|
| Age | ||||||
| Age<60 (n=41) | 38.4 (2.3-64.99) | 0.61a | 4.2 (3.4-15.7) | 0.89a | 156 (78-207) | 0.50a |
| Age≥60 (n=44) | 36.1 (2.95-67.4) | 4.2 (0.9-19.8) | 155.5 (12.7-218.0) | |||
| Residence | ||||||
| Rural (n=61) | 38.03 (3.99-67.4) | 0.16a | 4.2 (3.4-19.8) | 0.97a | 154 (12.7-218) | 0.28a |
| Urban (n=24) | 33.6 (2.3-62.7) | 4.2 (0.9-13.8) | 166.5 (28.8-198) | |||
| DM | ||||||
| Non Diabetic (n=71) | 36.2 (2.96-62.7) | 0.44a | 4.2 (0.9-19.8) | 0.78a | 156 (28.8-218) | 0.99a |
| Diabetic (n=14) | 44.1 (2.3-67.4) | 3.8 (3.4-15.7) | 160.5 (12.7-204) | |||
| BMI | ||||||
| Normal (n=27) | 29.6 (3.4-62.7) | 0.69b | 3.4 (3.4-7.4) | 0.63b | 162 (12.7- 207) | 0.68b |
| Overweight (n=38) | 36.1 (2.96-67.41) | 4.2 (0.9- 19.8) | 156 (28.8- 204) | |||
| Class I obesity (n=14) | 40.4 (2.3-59.5) | 4.2 (4.3.8-18.7) | 160.5 (33- 193) | |||
| Class II obesity (n=6) | 44.5 (4.02-55.5) | 3.8 (3.4-15.7) | 126 (43- 218) | |||
| Ascites | ||||||
| No (n=54) | 36.1 (2.3- 67.4) | 0.33a | 3.8 (3.4-19.8) | 0.32a | 155 (12.8- 218) | 0.61a |
| Yes (n=31) | 38.4 (2.96-64.99) | 4.2 (0.9-18.7) | 156.8 (78- 204) | |||
| Child-class | ||||||
| I (n=20) | 14.2 (2.3-59.5) | 0.03*b | 3.4 (3.4-6.6) | 0.53b | 170 (43-193) | 0.62b |
| II (n=45) | 40.8 (2.96- 67.4) | 4.2 (0.9- 19.8) | 151 (12.8- 218) | |||
| III (n=20) | 38.4 (4.3- 62.7) | 3.8 (3.4- 13.1) | 157.9 (33- 207) | |||
| Performance status (ECOG) | ||||||
| 0 (n=16) | 14.4 (4.02-58.3) | 0.02*b | 3.8 (3.4-8.1) | 0.74b | 168.5 (43.0-193.0) | 0.85b |
| 1 (n=22) | 37.2 (2.3-63.8) | 3.8 (0.9-19.8) | 152.5 (89.0-193.0) | |||
| 2 (n=34) | 38.6 (2.9- 67.4) | 4.2 (3.8-18.7) | 154 (12.7-198.0) | |||
| 3 (n=13) | 49.8 (9.5 -64.9) | 4.2 (3.4-13.7) | 159 (95- 218) | |||
| Number of lesions | ||||||
| Single (n=20) | 29.3 (2.3- 51.7) | 0.11b | 4.2 (3.2-18.7) | 0.006*b | 163.4 (12.7-187) | 0.70b |
| Bifocal (n=6) | 33.3 (7.8-55.5) | 6.2 (4.2-15.7) | 145.5 (100.6-180) | |||
| Multiple (n=59) | 38.9 (3.4-67.4) | 3.4 (0.9-19.8) | 156 (33- 218) | |||
| BCLC | ||||||
| A (n=3) | 35.9 (5.0- 36.03) | 0.38b | 4.2 (4.2-4.2) | 0.22b | 90 (86- 182) | 0.77b |
| B (n=27) | 37.8 (4.02-63.8) | 3.4 (3.4-15.7) | 152 (43- 198) | |||
| C (n=43) | 36.2 (2.3- 67.4) | 4.2 (0.9-19.8) | 165 (12.7- 218) | |||
| D (n=12) | 40.1 (4.8-64.9 | 4.2 (3.4- 13.7) | 152 (95- 207) | |||
| Tumor size(cm) | ||||||
| < 3 (n=8) | 36.9 (6.6- 55.5) | 0.21b | 4.2 (3.4- 15.7) | 0.30b | 139.5 (58- 182) | 0.14b |
| 3-5 (n=11) | 28.9 (2.3- 47.9) | 4.2 (3.4- 8.1) | 156 (28.8- 184) | |||
| > 5 (n=66) | 38.3 (2.9-67.4) | 3.4 (0.9-19.8) | 163.5 (12.7-218.0) | |||
| Metastasis | ||||||
| M0 (n=71) | 36.5 (2.3-67.4) | 0.66a | 4.2 (3.4- 18.7) | 0.39a | 152 (28.8- 207) | 0.20a |
| M1 (n=14) | 37.3 (7.8- 64.9) | 3.4 (0.9- 19.8) | 166.5 (12.7- 218) | |||
| Mortality | ||||||
| Alive (n=15) | 36.5 (4.02-60.75) | 0.73a | 4.2 (3.4- 15.7) | 0.64a | 109 (43- 182) | <0.001*a |
| Dead (n=70) | 37.2 (2.3-67.4) | 3.8 (0.9-19.8) | 165 (12.7-218.0) | |||
a, Mann whitney test; b, Kruskal Wallis test; *, Significance at p<0.05