Table 3.
Comparison between Patients with pCR and Patients without Regarding the Clinical Data
| pCR |
P- value | |||
|---|---|---|---|---|
| Yes n=56 | No n=24 | |||
| Menpausal | ||||
| Premenopausal =16pt. | 13 (30.2) | 3 (12.5) | 0.27 | |
| Postmenopausal =64pt. | 43 (69.8) | 21 (87.5) | ||
| BMI | ||||
| Normal BMI (Up to 25)= 36 pt. | 26 (46.4) | 10 (41.7) | 0.7 | |
| High BMI(more than 25) = 44pt | 30 (53.6) | 14 (58.3) | ||
| Histopathology | ||||
| IDC =75 pt | 53 (94.6) | 22 (91.7) | 0.61 | |
| ILC =5 pt | 3 (5.4) | 2 (8.3) | ||
| HER2 n (%) | ||||
| Positive = 17 pt | 10 (17.9) | 7 (29.2) | 0.26 | |
| Negative = 63 pt | 46 (82.1) | 17 (70.8) | ||
| ER status | ||||
| Positive =67 pt | 56 (100.0) | 11 (45.8) | < 0.001 | |
| Negative =13 pt | - | 13 (56.2) | ||
| PR status | ||||
| Positive = 51pt | 50 (89.3) | 1 (4.2) | < 0.001 | |
| Negative = 29 pt | 6 (10.7) | 23 (95.8) | ||
| Tumor grade n (%) | ||||
| Low = 5 pt | 5 (8.9) | 0 (0.00) | 0.004 | |
| Intermediate = 49 pt | 38 (67.9) | 11 (45.8) | ||
| High = 26 pt | 13 (23.2) | 13 (54.2) | ||
| Disease stage n (%) | ||||
| I = 21 pt | 16 (28.6) | 5 (20.8) | 0.12 | |
| II = 26 pt | 21 (37.5) | 5 (20.8) | ||
| IIIA = 33 pt | 19 (33.9) | 14 (58.4) | ||
| Ki-67 (%) median | 20.0 (5.0-48.8) | 15.0 (2.3-40.0) | 70.0 (30.0 – 80.0) | < 0.001 |
| LVI n (%) | 26 (32.5) | 15 (26.8) | 11 (45.8) | 0.1 |
| Disease status /Treatment outcome | ||||
| Relapse | 14(17.5) | 2(3.57) | 12 (50.0) | < 0.001 |
| Relapse free survival (months) median (IQR) | 14 (11.0 – 15.0) | 10 | 14 (12-15) | 0.17 |
| Survival time (months) median (IQR) | 35.0 (34.0-36.0) | 36.0 (35.0-37.0) | 31.0 (22.0-36.0) | < 0.001 |
| Mortality | 7 (8.8) | 1 (1.8) | 6 (25.0) | 0.001 |