Table 5.

Univariate and multivariate Cox regression analyses of the individual parameter for the correlations with overall survival rate of patients with CRC (n = 200).

Parameters	Univariate			Multivariate
	RR	95% CI for RR	P value	RR	95% CI for RR	P value
Gender	1.007	0.992–1.023	0.355	0.998	0.978–1.019	0.881
Age	1.408	0.958–2.068	0.081	1.152	0.755–1.758	0.512
Tumor size	1.551	1.367–1.758	0.000*	1.008	0.859–1.181	0.925
Differentiation	1.918	1.363–2.298	0.000*	1.025	0.682–1.542	0.904
Depth of invasion	7.570	3.529–16.238	0.000*	1.399	0.406–4.821	0.595
LN metastasis	70.668	17.003–293.710	0.000*	113,161.467	0.000–7.696E+59	0.857
Distant metastasis	24.300	13.926–42.402	0.000*	9.407	4.816–18.373	0.000*
TNM stage	1.118	1.078–1.160	0.000*	1.054	1.010–1.099	0.016*
circFADS2 expression	62.734	22.508–174.852	0.000*	6.228	1.287–30.131	0.023*

RR: relative risk; CI: confidence interval.

*Statistically significant difference (P < 0.05).