Comparison 3. Dual versus one antiplatelet agent for preventing early recurrence after ischaemic stroke or transient ischaemic attack.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
3.1 Stroke	13	13637	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.62, 0.80]
3.1.1 Aspirin + dipyridamole vs aspirin	5	977	Risk Ratio (M‐H, Fixed, 95% CI)	0.65 [0.38, 1.11]
3.1.2 Aspirin + dipyridamole vs clopidogrel	1	1360	Risk Ratio (M‐H, Fixed, 95% CI)	0.56 [0.27, 1.17]
3.1.3 Aspirin + clopidogrel vs aspirin	5	10739	Risk Ratio (M‐H, Fixed, 95% CI)	0.72 [0.63, 0.82]
3.1.4 Aspirin + clopidogrel vs clopidogrel	1	485	Risk Ratio (M‐H, Fixed, 95% CI)	0.85 [0.37, 1.97]
3.1.5 Aspirin + cilostazol vs aspirin	1	76	Risk Ratio (M‐H, Fixed, 95% CI)	0.25 [0.03, 2.13]
3.2 Vascular death	10	12831	Risk Ratio (M‐H, Fixed, 95% CI)	0.84 [0.54, 1.30]
3.2.1 Aspirin + dipyridamole vs aspirin	4	868	Risk Ratio (M‐H, Fixed, 95% CI)	0.65 [0.38, 1.11]
3.2.2 Aspirin + dipyridamole vs clopidogrel	1	1360	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
3.2.3 Aspirin + clopidogrel vs aspirin	4	10527	Risk Ratio (M‐H, Fixed, 95% CI)	1.37 [0.63, 2.98]
3.2.4 Aspirin + cilostazol vs aspirin	1	76	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable