Chairangsarit 2005.

Study characteristics
Methods	Randomised, open‐label, blind assessment
Participants	Participants with acute ischaemic stroke enrolled within 48 hours after clinical onset. Age should be more than 45 years. CT or MRI of the brain confirmed cerebral infarction and excluded haemorrhagic stroke or brain tumour. 38 participants were enrolled in the study (20 men, 18 women). Participants were followed up through clinic visits at 1 month, 3 months, and 6 months.
Interventions	Aspirin 300 mg once daily vs aspirin 300 mg once daily plus dipyridamole 75 mg 3 times a day
Outcomes	Primary outcome: recurrent ischaemic stroke and TIA Secondary outcome: vascular death due to MI or any type of stroke
Notes	During the 9‐month screening period, 39 of 60 eligible participants were recruited and followed up for 6 months.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Blinded randomisation
Allocation concealment (selection bias)	Low risk	Methods described
Blinding of participants and personnel (performance bias) All outcomes	High risk	Participant is aware of treatment
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Blind outcome assessment
Incomplete outcome data (attrition bias) All outcomes	High risk	11 of 38 (28.9%) participants lost to follow‐up
Selective reporting (reporting bias)	Low risk	All expected outcomes reported