Petrovska‐Cvetkovska 2008.

Study characteristics
Methods	Randomised, open‐label. Unclear outcome assessment blinding and allocation concealment
Participants	Participants had a history of TIA, were randomised within the first 24 hours. 40 participants received aspirin 75 mg + clopidogrel 75 mg and 44 received aspirin (100 mg to 325 mg) alone.
Interventions	1 group received oral aspirin 75 mg and oral clopidogrel 75 mg once daily while the other group received oral aspirin 100 mg to 325 mg alone. Participants were followed up for 1 year.
Outcomes	Primary outcome: recurrent TIA or stroke Secondary: intracranial or systemic adverse effects
Notes	2 other groups received statins
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not mentioned
Allocation concealment (selection bias)	Unclear risk	Not mentioned
Blinding of participants and personnel (performance bias) All outcomes	High risk	Open‐label trial
Blinding of outcome assessment (detection bias) All outcomes	High risk	Open‐label trial
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not clearly described
Selective reporting (reporting bias)	Unclear risk	Not clearly described