Comparison 11. Adolescent ‐ Metformin versus OCP (Hormonal parameters).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
11.1 Serum total testosterone (nmol/L)	3	69	Mean Difference (IV, Fixed, 95% CI)	0.23 [‐0.21, 0.68]
11.1.1 BMI ≥ 30 kg/m2	3	69	Mean Difference (IV, Fixed, 95% CI)	0.23 [‐0.21, 0.68]
11.2 Free androgen index (FAI) (%)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
11.2.1 BMI ≥ 30 kg/m2	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected