Table II.

Microbiology finding of synovial fluid culture, periprosthetic tissue culture, comprehensive culture, and synovial fluid metagenomic next-generation sequencing.

Microorganism	No. of isolates from synovial fluid culture	No. of isolates from periprosthetic tissue	No. of isolates from comprehensive culture	No. of identifications from synovial fluid by mNGS
Coagulase-negative staphylococci	10	10	13	13
Staphylococcus aureus	7	8	8	8
Anaerobe*	2	2	2	5
Streptococci	5	5	5	6
Gram-negative bacilli	3	3	4	5
Mycoplasma†	0	0	0	4
Enterococcus faecalis	3	3	5	3
Candida‡	3	5	5	4
Mycobacterium	0	1	1	2
Other organisms§	1	2	2	3
Total	34	39	45	53

^*Including Parvimonas micra, Bacteroides fragilis, and Cutibacterium acnes.

^†Including Mycoplasma hominis.

^‡Including Candida albicans, Candida parapsilosis, and Candida tropicalis.

^§Including Neisseria spp., Helcococcus kunzii, and Corynebacterium tuberculostearicum.

mNGS, metagenomic next-generation sequencing.