Table 2.

Results of the co-relative analysis of the association between academic achievement and alcohol use disorder

		Alcohol use disorder
Sample	Sample size, n	Observed HR [95% CI]	Predicted HR [95% CI]
Population	929,437	2.14 [2.11, 2.17]	2.13 [2.10, 2.15]
Cousins	523,245	1.97 [1.93, 2.02]	2.03 [2.00, 2.05]
Full siblings	305,337	1.77 [1.72, 1.83]	1.75 [1.70, 1.80]
Monozygotic twins	2,193	1.95 [0.91, 4.16]	1.44 [1.35, 1.52]
AIC		673,925.97	673,927.52
Males
Population	475,519	2.27 [2.23, 2.30]	2.26 [2.22, 2.29]
Cousins	136,971	2.08 [2.00, 2.15]	2.17 [2.14, 2.21]
Full siblings	80,189	1.99 [1.88, 2.11]	1.93 [1.84, 2.03]
Monozygotic twins	981	1.22 [0.52, 2.87]	1.66 [1.49, 1.84]
AIC		434,559.46	434,560.78
Females
Population	453,918	2.00 [1.94, 2.03]	2.00 [1.95, 2.04]
Cousins	125,251	1.90 [1.81, 2.01]	1.89 [1.85, 1.94]
Full siblings	73,071	1.60 [1.48, 1.72]	1.61 [1.50, 1.73]
Monozygotic twins	1,212	4.09 [0.64, 26.1]	1.30 [1.12, 1.51]
AIC		186,374.07	186,371.89

Notes: HR = hazard ratio; CI = confidence interval; AIC = Akaike information criterion.