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NT-3 enhances ordinate and oriented axonal elongation.
A double immunofluorescence for both neurons (β-tubulin, green) and satellite cells (S-100, red) showed linear and oriented axon growth in the presence of NT-3. When anti-NT-3 antibody was added to the medium, the linearity of axonal growth was lost and the feature of a cell cluster was depicted again (inset). Scale bars: 100 µm for and inset. NT-3: Neurotrophin-3.
