Table 1.

Potential neuroepigenetic targets of spinal cord injury

Targets	References
Axon regeneration
Histone acetylation
AcH4	Finelli et al. (2013)
H3K9ac	Puttagunta et al. (2014)
CTCF	Palmisano et al. (2019)
P/CAF	Puttagunta et al. (2014)
H3K4me3	Venkatesh et al. (2016)
Histone deacetylation
HDAC-I	Lv et al. (2012)
HDAC5	Weng et al. (2016)
pan-HDAC	Finelli et al. (2013); Li et al. (2015)
DNA methylation
DNMT1	Endres et al. (2000)
DNMT3 A/B	Kronenberg and Endres (2010)
MeCP2	Shah and Bird (2017); Horvath and Monteggia (2018)
DNA demethylation
GADD45	Befort et al. (2003); Lindner et al. (2013)
Tets	Perera et al. (2015); Weng et al. (2017)
Cytoskeleton deacetylation
Actin	Gao et al. (2007)
α-Tubulin	Dan et al. (2018)
MicroRNAs & RBPs
miR-133b	Yu et al. (2011); Lu et al. (2015)
miR-210	Hu et al. (2013); Hu et al. (2016)
mir-26a	Jiang et al. (2015)
miR-138	Liu et al. (2013)
miR-132	Yunta et al. (2012); Hancock et al. (2014)
Lin28 (RBPs)	Wang et al. (2018)
Secondary SCI reaction
Oligodendrocytes
SIRT2	Li et al. (2007)
EZH2 (PRC2)	Sher et al. (2008)
HDACs	Conway et al. (2012)
H3K27me3	He et al. (2017)
HDAC1/2	Shen et al. (2008)
miR-219	Dugas et al. (2010)
miR-138	Emery and Lu (2015)
Astrocytes
HDACs	Schmidt et al. (2011)
miR-21	Bhalala et al. (2012); Zhang et al. (2019)
EZH2	Hwang et al. (2014)
GASC1	Sudo et al. (2016)
Microglias & immune system
HDAC3	Mullican et al. (2011)
JMJD3	Lee et al. (2016)
miR-136-5p	Yin et al. (2017); Deng et al. (2018); Lankford et al. (2018)
Neuroprotection
DNMTS	Chestnut et al. (2011); Wong et al. (2013)
miR-210	Ujigo et al. (2014)
HDAC3	Lankford et al. (2018)

DNMT: DNA methyltransferase family enzyme; HDAC: histone deacetylase; MeCP2: methyl CpG-binding protein 2; P/CAF: p300/CBP-associated factor; RBP: RNA-binding protein.