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American College of Medical Genetics and Genomics Variant Classifications
| Classification | Meaning |
|---|---|
| Pathogenic | Disease-causing |
| Likely pathogenic | >90% chance variant is disease-causing |
| Variant of uncertain significance | Uncertain whether variant is disease-causing |
| Likely benign | >90% chance variant is not disease-causing |
| Benign | Not disease-causing |
