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. 2020 Aug 18;5(4):e000866. doi: 10.1136/esmoopen-2020-000866

Table 4.

Other AEs grouped into major organ systems in patients treated with PD-1/PDL-1 inhibitors

TB death events (n=13) TB alive events (n=59) TB total
(n=72)
AMI death events (n=1) AMI alive events (n=12) AMI total
(n=13)
Pulmonary 5 (38.46%) 9 (15.25%) 14 (19.44%) 0 5 (41.66%) 5 (38.46%)
Infectious 3 (23.07%) 7 (11.86%) 10 (13.88%) 1 (100%) 0 1 (7.69%)
Endocrine 0 5 (8.47%) 5 (6.94%) 0 2 (16.66%) 2 (15.38%)
Gastrointestinal 2 (15.38%) 3 (5.08%) 5 (6.94%) 0 1 (8.33%) 1 (7.69%)
Hepatobiliary 1 (7.69%) 4 (6.77%) 5 (6.94%) 0 0 0
Cardiac 0 4 (6.77%) 4 (5.55%) 0 0 0
Haematological 0 3 (5.08%) 3 (4.16%) 0 0 0
Dermatological 0 3 (5.08%) 3 (4.16%) 0 2 (16.66%) 2 (15.38%)
Neurological 0 3 (5.08%) 3 (4.16%) 0 0 0
Vascular 1 (7.69%) 1 (1.69%) 2 (2.77%) 0 0 0
Infusion related 1 (7.69%) 0 1 (1.38%) 0 0 0
Rheumatological 0 1 (1.69%) 1 (1.38%) 0 0 0
Others 1 (7.69%) 4 (6.77%) 5 (6.94%) 1 (100%) 1 (8.33%) 2 (15.38%)

AEs, adverse events; AMI, atypical mycobacterial infection; PD-1, programmed cell death-1; PD-L1, programmed cell death ligand-1; TB, tuberculosis.