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. Author manuscript; available in PMC: 2021 Jul 9.
Published in final edited form as: J Med Chem. 2020 Jun 18;63(13):6979–6990. doi: 10.1021/acs.jmedchem.0c00180

Figure 5.

Figure 5.

cy(WPHPY) inhibited cell migration. (a) Schematic illustration of the scratch wound-healing experiment. (b) Results of the scratch wound-healing experiment demonstrate that cy(WPHPY) treatments led to fewer cells migrating to the scratch wound. (c) Schematic illustration of the transwell cell invasion assay. Active MMP2 was required for the cells to digest the Matrigel and invade through the porous membrane. Before the final imaging stage, cells were fixed and stained with crystal violet. (d) Results of the transwell assay demonstrate that cy(WPHPY) significantly inhibited cell invasion. Images were taken after 24 h of incubation.