Table 1:

Pharmacokinetic parameters and IC₅₀ of vinpocetine.

Volume of distribution	3.2 ± 0.9 L/kg	Intravenous single bolus injection of 10mg in young healthy human subjects	[3,4]
Total plasma clearance	0.88 ± 0.20 L/hour/kg
Elimination half-life (t1/2)	1–2 hours	Intravenous single bolus injection of 10mg in young healthy human subjects	[3]
		3X5 and 3X10 mg tablet daily doses for seven days in young healthy human subjects	[2]
IC50	PDE1A, PDE1B	8–20 uM	[7–9]
	PDE1C	40–50 uM	[7,8]
	Voltage-gated Na+ channel	10–50 uM	[10–14]
	IKK	17.17 uM	[15]