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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: ACS Nano. 2020 Jun 23;14(7):8392–8408. doi: 10.1021/acsnano.0c02509

Figure 1. HMC-FMX facilitates GBM tumor detection and drug delivery across the BBB.

Figure 1.

(a). HMC-FMX accumulates in GBM tumors via OATP transport following intravenous administration, and the accumulated HMC-FMX can be detected by a fluorescence imaging camera (b). As FMX can also encapsulate chemotherapeutic drugs, drug-loaded HMC-FMX nanoprobes can identify tumors and then deliver chemotherapeutic drugs across the BBB into any remaining GBM tumor tissue following surgery (c).