Table II:

Multivariable proportional hazard models demonstrating the association between clinical factors and overall survival. Model I includes patient age and the number of comorbidities. Model II adds the prostate cancer risk group / stage information. Finally, model III incorporates race/ethnicity. The fit of each model is included as the C-index.

	Model I Age and Comorbidity	Model II Age, Comorbidity, and Risk Group	Model III Age, Comorbidity, Risk Group, and Race/ethnicity
	HR (CI)	HR (CI)	HR (CI)
Age (per 5 year increase) Number of Comorbidities	1.39 (1.39–1.40)	1.32 (1.31–1.33)	1.40 (1.39–1.40)
0	Ref	Ref	Ref
1	1.15 (1.12–1.17)	1.20 (1.17–1.22)	1.20 (1.17–1.22)
2	1.53 (1.50–1.57)	1.60 (1.57–1.64)	1.60 (1.56–1.64)
3	2.05 (1.99–2.10)	2.12 (2.07–2.18)	2.12 (2.06–2.18)
4	2.67 (2.57–2.77)	2.69 (2.59–2.79)	2.68 (2.59–2.78)
5	3.38 (3.20–3.57)	3.38 (3.20–3.57)	3.37 (3.19–3.56)
6	3.64 (3.32–3.99)	3.55 (3.24–3.89)	3.54 (3.23–3.88)
7+	6.01 (5.27–6.85)	5.46 (4.79–6.23)	5.45 (4.78–6.22)
Risk Group
Low		Ref	Ref
Intermediate		1.31 (1.28–1.34)	1.31 (1.28–1.34)
High		1.49 (1.46–1.52)	1.48 (1.46–1.51)
Locally Advanced		2.72 (2.56–2.88)	2.72 (2.56–2.88)
Metastatic		5.94 (5.79–6.10)
Race/ethnicity			Ref
White			5.92 (5.77–6.08)
Black			1.03 (1.01–1.05)
Other			0.88 (0.81–0.96)
Missing			0.95 (0.91–1.00)
C-index	0.678	0.729	0.738