Table 3.

Difference (‘delta’) scores of NPA Z-scores in normal and high concentration of EFV groups within the switch group

Type of NPA Z-score	Concentration EFV < 4.0 mg/L	Concentration EFV ≥ 4.0 mg/L	p value
Composite median (IQR)	0.22 (0.54)	0.58 (0.32)	0.15
Domain verbal	0.15 ± 0.64	0.47 ± 0.42	0.63
Domain memory	− 0.24 ± 0.49	− 0.03 ± 0.73	0.48
Domain executive functioning	0.42 ± 0.52	0.33 ± 0.30	0.82
Domain attention	0.46 ± 0.60	0.98 ± 0.67	0.33
Domain speed	0.42 ± 0.41	0.93 ± 0.73	0.05
Domain motor	0.54 ± 0.85	0.80 ± 0.36	0.18
Domain learning	0.41 ± 1.00	0.80 ± 0.31	0.65

Values shown as mean ± SD, unless otherwise specified

*Difference between groups considered significant (p value < 0.05)

NPA neuropsychological assessment, EFV efavirenz, IQR interquartile range, SD standard deviation