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Comparison of sensitivity of Gen 2 and Gen 3 SID devices on the FT-ICR using streptavidin in EDDA (mainly 12+ and 13+ precursors, no isolation): (a) Comparison of flythrough and SID intensities under comparable conditions, and (b) comparison of representative SID spectra at 40 V acceleration (Q (tetramer) produces two dimers, D (e.g., Q12+ → 2 D6+ and Q13+ → D6+ plus D7+), and monomer (M) plus trimer (T).)
