Table 5.

Risk factors for reoperation across all segments of the aorta and late mortality (multivariable Cox proportional hazard regression)

	HR (95% CI)	p-value
Root reoperation (among native root patients)
Pathogenic	13.1 (3.4, 51.1)	0.0002
Age	1.0 (1.0, 1.1)	0.62
Type A dissection	1.3 (0.4, 4.2)	0.62
Hypertension	0.5 (0.2, 1.7)	0.28
Arch reoperation (among native arch patients)
Pathogenic	3.8 (0.7, 21.3)	0.13
Age	1.0 (0.9, 1.0)	0.64
Type A dissection	6.1 (0.7, 51.7)	0.10
Hypertension	5.8 (1.5, 22.7)	0.01
Descending reoperation (stratified by type A)
Pathogenic	1.7 (0.8, 3.8)	0.17
Age	1.01 (0.98, 1.03)	0.66
Aggressive arch replacement	1.3 (0.6, 3.0)	0.55
Hypertension	1.4 (0.7, 2.7)	0.38
Abdominal reoperation (stratified by arch procedure)
Pathogenic	0.8 (0.1, 9.4)	0.85
Age	1.0 (0.9, 1.1)	0.92
Type A dissection	1.0 (0.2, 4.8)	0.97
Hypertension	1.6 (0.2, 10.4)	0.64
Late mortality
Pathogenic	1.8 (0.4, 7.0)	0.42
Female sex	3.4 (1.4, 8.3)	0.008
Age	1.1 (1.0, 1.1)	<0.0001
Hypertension	1.3 (0.5, 3.5)	0.65
Type A dissection	1.4 (0.5, 3.8)	0.46

CI=confidence interval; HR=hazard ratio