Table 4.

Correlations of qualitative grades with changes in quantitative parameters at each time with maximum symptoms

	Peak time	Erythema index	Skin temperature	Capacitance	TEWL	Melanin index
CTCAE	Week 5	0.40*	− 0.005	0.27	− 0.32*	0.19
	Week 7			0.08	− 0.1	0.083
	Week 11			0.27
Erythema	Week 5	0.35*	0.19
Skin dryness	Week 7			− 0.32*	− 0.22
Pigmentation	Week 7					0.50**

Values are shown as correlation coefficients, which were determined using Spearman’s correlation test

CTCAE Common Terminology Criteria for Adverse Events, temp temperature, TEWL transepidermal water loss

*p < 0.05, **p < 0.01